ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: leucine proline-enriched proteoglycan (leprecan) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296388 LEPRE1-001 ENSG00000117385 9606 - 1:42746375-42767023 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000296388
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000296388 25.727±8.58 41.516±14.11 32.078±0.00 40.458±24.92

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005506 IEA iron ion binding
GO:0005518 ISS collagen binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005783 IDA endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0006457 IMP protein folding
GO:0008285 NAS negative regulation of cell proliferation
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018126 IMP protein hydroxylation
GO:0019511 IEA peptidyl-proline hydroxylation
GO:0019797 ISS procollagen-proline 3-dioxygenase activity
GO:0030198 TAS extracellular matrix organization
GO:0031418 IEA L-ascorbic acid binding
GO:0032403 ISS protein complex binding
GO:0032963 ISS collagen metabolic process
GO:0032991 ISS macromolecular complex
GO:0050708 IMP regulation of protein secretion
GO:0050821 IMP protein stabilization
GO:0055114 IEA oxidation-reduction process
GO:0060348 IMP bone development
GO:0061077 ISS chaperone-mediated protein folding
GO:0070062 IDA extracellular vesicular exosome
GO:1901874 IMP negative regulation of post-translational protein modification

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000121111 P3h1-001 protein_coding Mus_musculus 0 2639
ENSMUST00000030393 P3h1-012 protein_coding Mus_musculus 0 2553
ENSMUST00000102662 P3h1-003 protein_coding Mus_musculus 0 2514
ENSMUST00000081606 P3h1-007 protein_coding Mus_musculus 0 2287
ENSMUST00000153940 P3h1-002 processed_transcript Mus_musculus 0 1825
ENSMUST00000136278 P3h1-004 nonsense_mediated_decay Mus_musculus 0 1312
ENSMUST00000131875 P3h1-005 processed_transcript Mus_musculus 0 767
ENSMUST00000127087 P3h1-009 retained_intron Mus_musculus 0 477
ENSMUST00000123963 P3h1-011 processed_transcript Mus_musculus 0 401
ENSMUST00000126056 P3h1-006 processed_transcript Mus_musculus 0 401
ENSMUST00000142361 P3h1-010 processed_transcript Mus_musculus 3.00018e-42 178

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