ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: SIX homeobox 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000303077 SIX2-001 ENSG00000170577 9606 - 2:45005161-45009430 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000303077
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000303077 0.707±0.16 0.860±0.44 0.255±0.00 0.311±0.49

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001656 IEA metanephros development
GO:0001822 ISS kidney development
GO:0002062 IEA chondrocyte differentiation
GO:0003337 ISS mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006606 IEA protein import into nucleus
GO:0007501 ISS mesodermal cell fate specification
GO:0008134 IEA transcription factor binding
GO:0008283 IDA cell proliferation
GO:0009653 TAS anatomical structure morphogenesis
GO:0009948 ISS anterior/posterior axis specification
GO:0016477 IDA cell migration
GO:0030278 IEA regulation of ossification
GO:0032330 IEA regulation of chondrocyte differentiation
GO:0032403 IEA protein complex binding
GO:0042474 IEA middle ear morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045596 IEA negative regulation of cell differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048557 ISS embryonic digestive tract morphogenesis
GO:0048701 IEA embryonic cranial skeleton morphogenesis
GO:0048704 IEA embryonic skeletal system morphogenesis
GO:0072006 ISS nephron development
GO:0072028 ISS nephron morphogenesis
GO:0072038 ISS mesenchymal stem cell maintenance involved in nephron morphogenesis
GO:0072161 ISS mesenchymal cell differentiation involved in kidney development
GO:0090189 ISS regulation of branching involved in ureteric bud morphogenesis
GO:0097168 ISS mesenchymal stem cell proliferation
GO:1902732 ISS positive regulation of chondrocyte proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000163568 Six2-001 protein_coding Mus_musculus 0 1465
ENSMUST00000024947 Six2-201 protein_coding Mus_musculus 0 1461
ENSMUST00000050029 Six1-001 protein_coding Mus_musculus 0 676
ENSMUST00000175693 Six4-002 protein_coding Mus_musculus 0 239
ENSMUST00000043208 Six4-001 protein_coding Mus_musculus 0 239
ENSDART00000078064 six9-201 protein_coding Danio_rerio 5.04467e-44 183
ENSDART00000126421 six9-001 protein_coding Danio_rerio 5.04467e-44 183
ENSMUST00000049454 Six5-001 protein_coding Mus_musculus 1e-30 139

Loading