ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: phosphodiesterase 5A, cGMP-specific
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354960 PDE5A-001 ENSG00000138735 9606 - 4:119494395-119628991 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000354960
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000354960 0.164±0.00 0.587±0.33 1.035±0.00 0.488±0.29

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004112 IEA cyclic-nucleotide phosphodiesterase activity
GO:0004114 NAS:IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0005575 ND cellular_component
GO:0005829 TAS cytosol
GO:0007165 IEA signal transduction
GO:0007596 TAS blood coagulation
GO:0010613 IEA positive regulation of cardiac muscle hypertrophy
GO:0030553 TAS cGMP binding
GO:0030823 IEA regulation of cGMP metabolic process
GO:0042130 IEA negative regulation of T cell proliferation
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0046068 IEA cGMP metabolic process
GO:0046069 IEA cGMP catabolic process
GO:0046872 IEA metal ion binding
GO:0047555 IEA 3',5'-cyclic-GMP phosphodiesterase activity
GO:0055118 IEA negative regulation of cardiac muscle contraction
GO:0055119 IEA relaxation of cardiac muscle
GO:0060282 IEA positive regulation of oocyte development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066728 Pde5a-001 protein_coding Mus_musculus 0 3205

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