ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: apoptotic peptidase activating factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000357310 APAF1-202 ENSG00000120868 9606 + 12:98645300-98735426 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000357310
Transcript ID HAoEC HUVEC
ENST00000357310 3.038±0.09 0.761±0.54

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 TAS nucleotide binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007399 TAS nervous system development
GO:0008635 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008656 NAS cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0042981 TAS:IEA regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043293 TAS apoptosome
GO:0043531 IEA ADP binding
GO:0070062 IDA extracellular vesicular exosome
GO:0072432 TAS response to G1 DNA damage checkpoint signaling
GO:0097193 TAS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020157 Apaf1-001 protein_coding Mus_musculus 0 2813
ENSMUST00000159110 Apaf1-002 protein_coding Mus_musculus 0 2813
ENSMUST00000162618 Apaf1-003 protein_coding Mus_musculus 0 2545
ENSMUST00000160725 Apaf1-008 retained_intron Mus_musculus 3e-31 143
ENSMUST00000105321 Nfic-001 protein_coding Mus_musculus 0.0000002 64
ENSMUST00000091246 Flcn-005 protein_coding Mus_musculus 0.00001 58
ENSMUST00000148151 Flcn-003 retained_intron Mus_musculus 0.00001 58
ENSMUST00000102697 Flcn-004 protein_coding Mus_musculus 0.00001 58

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