ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102697 Flcn-004 ENSMUSG00000032633 10090 - 11:59791408-59810016 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000102697
Transcript ID C166 Tie2+ EC mES
ENSMUST00000102697 6.039±0.58 3.979±2.82 5.795±1.57

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001701 IMP in utero embryonic development
GO:0001932 ISS regulation of protein phosphorylation
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005886 ISS plasma membrane
GO:0007043 IMP cell-cell junction assembly
GO:0010629 IMP negative regulation of gene expression
GO:0010823 IMP negative regulation of mitochondrion organization
GO:0016525 NAS negative regulation of angiogenesis
GO:0030097 IMP hemopoiesis
GO:0030308 ISS negative regulation of cell growth
GO:0030336 ISS negative regulation of cell migration
GO:0030496 ISS midbody
GO:0030511 IMP positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031929 ISS TOR signaling
GO:0032006 IMP regulation of TOR signaling
GO:0032007 IMP negative regulation of TOR signaling
GO:0032008 IMP positive regulation of TOR signaling
GO:0032403 ISS protein complex binding
GO:0032465 ISS regulation of cytokinesis
GO:0035024 ISS negative regulation of Rho protein signal transduction
GO:0035065 IMP regulation of histone acetylation
GO:0044291 ISS cell-cell contact zone
GO:0045785 ISS positive regulation of cell adhesion
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0070373 IMP negative regulation of ERK1 and ERK2 cascade
GO:1900181 ISS negative regulation of protein localization to nucleus
GO:1901723 IMP negative regulation of cell proliferation involved in kidney development
GO:1901856 IMP negative regulation of cellular respiration
GO:1901859 IMP negative regulation of mitochondrial DNA metabolic process
GO:1901862 IMP negative regulation of muscle tissue development
GO:1901874 IMP negative regulation of post-translational protein modification
GO:2000506 IMP negative regulation of energy homeostasis
GO:2000973 IMP regulation of pro-B cell differentiation
GO:2001170 IMP negative regulation of ATP biosynthetic process
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262878 SAMHD1-001 protein_coding Homo_sapiens 0.0000001 64
ENST00000264990 ACAD11-001 protein_coding Homo_sapiens 0.000006 58
ENST00000285071 FLCN-001 protein_coding Homo_sapiens 0 2025
ENST00000298912 CLMN-001 protein_coding Homo_sapiens 0.00006 57
ENST00000317233 AFF3-201 protein_coding Homo_sapiens 0.00004 57
ENST00000333991 APAF1-201 protein_coding Homo_sapiens 0.000006 58
ENST00000355086 SRGAP1-001 protein_coding Homo_sapiens 0.000009 60
ENST00000357310 APAF1-202 protein_coding Homo_sapiens 0.00001 58
ENST00000359972 APAF1-001 protein_coding Homo_sapiens 0.00001 58
ENST00000366398 RP5-886K2.1-001 processed_pseudogene Homo_sapiens 0.0000001 62
ENST00000371655 RAB3B-001 protein_coding Homo_sapiens 0.0000004 64
ENST00000378823 RAD50-001 protein_coding Homo_sapiens 0.0000003 64
ENST00000389168 FLCN-004 retained_intron Homo_sapiens 0 481
ENST00000389169 FLCN-002 protein_coding Homo_sapiens 0 1099
ENST00000389171 FLCN-003 retained_intron Homo_sapiens 0 481
ENST00000397802 POLR3D-001 protein_coding Homo_sapiens 0.000008 58
ENST00000409236 AFF3-001 protein_coding Homo_sapiens 0.00005 57
ENST00000414513 CD99P1-002 retained_intron Homo_sapiens 0.0002 53
ENST00000417064 FLCN-006 protein_coding Homo_sapiens 0 665
ENST00000427497 RP11-45M22.4-001 nonsense_mediated_decay Homo_sapiens 0 571
ENST00000466317 FLCN-005 retained_intron Homo_sapiens 0 311
ENST00000469222 SAG-006 retained_intron Homo_sapiens 0.0003 53
ENST00000471702 NPHP3-ACAD11-001 nonsense_mediated_decay Homo_sapiens 0.00001 58
ENST00000478816 KCTD18-003 retained_intron Homo_sapiens 0.0002 53
ENST00000480316 FLCN-009 retained_intron Homo_sapiens 0 580
ENST00000485198 ACAD11-002 nonsense_mediated_decay Homo_sapiens 0.000004 58
ENST00000486943 CACNA1F-005 protein_coding Homo_sapiens 0.00000002 64
ENST00000493286 PPARA-005 retained_intron Homo_sapiens 0.000002 58
ENST00000493357 MIER1-005 processed_transcript Homo_sapiens 0.0000006 58
ENST00000496418 ACAD11-006 retained_intron Homo_sapiens 0.000005 58
ENST00000510852 USP53-004 retained_intron Homo_sapiens 0.00000007 64
ENST00000527788 QSER1-002 protein_coding Homo_sapiens 0.0000005 62
ENST00000550527 APAF1-004 protein_coding Homo_sapiens 0.000009 58
ENST00000577307 CCT6B-004 retained_intron Homo_sapiens 0.0000004 62
ENST00000588555 SCAMP4-002 retained_intron Homo_sapiens 0.0000002 62
ENST00000595101 USE1-002 protein_coding Homo_sapiens 0.0000007 60
ENST00000599380 SLC27A1-004 nonsense_mediated_decay Homo_sapiens 0.00005 55
ENST00000615596 GTF2I-009 retained_intron Homo_sapiens 0.000000006 66

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