ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: growth factor receptor-bound protein 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000398810 GRB10-202 ENSG00000106070 9606 - 7:50590063-50705301 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


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Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000398810
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000398810 10.582±2.68 10.007±0.00 7.424±2.89

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005158 ISS insulin receptor binding
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0007165 IEA signal transduction
GO:0008286 ISS insulin receptor signaling pathway
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030949 IDA positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032868 ISS response to insulin
GO:0042327 ISS positive regulation of phosphorylation
GO:0045719 ISS negative regulation of glycogen biosynthetic process
GO:0046325 ISS negative regulation of glucose import
GO:0046627 ISS negative regulation of insulin receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109654 Grb10-009 protein_coding Mus_musculus 0 1554
ENSMUST00000093321 Grb10-005 protein_coding Mus_musculus 0 1435
ENSMUST00000109653 Grb10-004 protein_coding Mus_musculus 0 813
ENSMUST00000142877 Grb10-006 processed_transcript Mus_musculus 0 222
ENSMUST00000143386 Grb10-003 protein_coding Mus_musculus 5e-32 145
ENSMUST00000150972 Grb10-001 protein_coding Mus_musculus 5e-32 145
ENSMUST00000143915 Grb10-002 protein_coding Mus_musculus 4e-28 132

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