ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: hypermethylated in cancer 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000619757 HIC1-006 ENSG00000177374 9606 + 17:2055099-2063241 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HUVECENST00000619757
Transcript ID HUVEC
ENST00000619757 1.289±0.40

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA:ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000785 ISS chromatin
GO:0003700 IEA:IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0007275 IEA multicellular organismal development
GO:0008630 IEA:IDA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016055 IEA Wnt signaling pathway
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0042826 IDA histone deacetylase binding
GO:0043517 ISS positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043565 IDA sequence-specific DNA binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000055619 Hic1-001 protein_coding Mus_musculus 0 2833
ENSMUST00000131720 Hic1-002 processed_transcript Mus_musculus 0 592
ENSMUST00000130145 Smg6-003 nonsense_mediated_decay Mus_musculus 0 544
ENSMUST00000045281 Smg6-001 protein_coding Mus_musculus 0 544
ENSMUST00000153226 Smg6-006 processed_transcript Mus_musculus 0 464

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