ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: SH3 and multiple ankyrin repeat domains 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000391813 SHANK1-003 ENSG00000161681 9606 - 19:50661827-50689404 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000391813
Transcript ID BECs HAoEC HUVEC
ENST00000391813 0.189±0.10 0.328±0.00 0.017±0.01

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005622 NAS intracellular
GO:0005737 IEA cytoplasm
GO:0005886 ISS plasma membrane
GO:0006461 ISS protein complex assembly
GO:0007016 NAS cytoskeletal anchoring at plasma membrane
GO:0007616 ISS long-term memory
GO:0008022 ISS protein C-terminus binding
GO:0008306 ISS associative learning
GO:0008328 ISS ionotropic glutamate receptor complex
GO:0016020 IDA membrane
GO:0017124 ISS SH3 domain binding
GO:0017146 ISS N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0030160 ISS GKAP/Homer scaffold activity
GO:0030425 NAS dendrite
GO:0030534 IMP adult behavior
GO:0031877 ISS somatostatin receptor binding
GO:0032232 ISS negative regulation of actin filament bundle assembly
GO:0032403 ISS protein complex binding
GO:0035176 IMP social behavior
GO:0035255 ISS ionotropic glutamate receptor binding
GO:0035418 ISS protein localization to synapse
GO:0042802 ISS identical protein binding
GO:0043005 ISS neuron projection
GO:0043197 ISS dendritic spine
GO:0045211 ISS postsynaptic membrane
GO:0050885 ISS neuromuscular process controlling balance
GO:0050894 IMP determination of affect
GO:0060074 ISS synapse maturation
GO:0060076 ISS excitatory synapse
GO:0060997 ISS dendritic spine morphogenesis
GO:0060999 ISS positive regulation of dendritic spine development
GO:0071532 ISS ankyrin repeat binding
GO:0071625 IMP vocalization behavior
GO:0097110 ISS scaffold protein binding
GO:0097481 ISS neuronal postsynaptic density
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107935 Shank1-003 protein_coding Mus_musculus 0 4602
ENSMUST00000107938 Shank1-001 protein_coding Mus_musculus 0 4492
ENSMUST00000107934 Shank1-002 protein_coding Mus_musculus 0 4377
ENSMUST00000154776 Shank1-004 retained_intron Mus_musculus 0 904
ENSMUST00000127164 Shank1-007 retained_intron Mus_musculus 0 592
ENSMUST00000134470 Shank1-005 processed_transcript Mus_musculus 0 592
ENSMUST00000134205 Shank1-006 processed_transcript Mus_musculus 0 287

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