ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: tropomyosin 1 (alpha)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000358278 TPM1-018 ENSG00000140416 9606 + 15:63042685-63071889 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000358278
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000358278 127.476±0.00 61.578±27.99 120.671±0.00 173.694±98.07

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0001725 IDA stress fiber
GO:0003065 ISS positive regulation of heart rate by epinephrine
GO:0003779 TAS actin binding
GO:0005200 TAS structural constituent of cytoskeleton
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0005862 TAS muscle thin filament tropomyosin
GO:0006928 TAS cellular component movement
GO:0006936 TAS muscle contraction
GO:0006937 TAS regulation of muscle contraction
GO:0007010 TAS cytoskeleton organization
GO:0008016 TAS regulation of heart contraction
GO:0008092 IPI cytoskeletal protein binding
GO:0008307 TAS structural constituent of muscle
GO:0030016 IEA myofibril
GO:0030017 TAS sarcomere
GO:0030049 ISS muscle filament sliding
GO:0030336 ISS negative regulation of cell migration
GO:0031529 ISS ruffle organization
GO:0031941 IEA filamentous actin
GO:0032059 IMP bleb
GO:0032587 IDA ruffle membrane
GO:0032781 ISS positive regulation of ATPase activity
GO:0034614 IEP cellular response to reactive oxygen species
GO:0042060 ISS wound healing
GO:0045214 IMP sarcomere organization
GO:0045785 ISS positive regulation of cell adhesion
GO:0051496 ISS positive regulation of stress fiber assembly
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113697 Tpm1-006 protein_coding Mus_musculus 0 1709
ENSMUST00000113707 Tpm1-001 protein_coding Mus_musculus 0 1565
ENSMUST00000113701 Tpm1-010 protein_coding Mus_musculus 0 1330
ENSMUST00000050905 Tpm1-004 protein_coding Mus_musculus 0 1325
ENSMUST00000113705 Tpm1-007 protein_coding Mus_musculus 0 1271
ENSMUST00000034928 Tpm1-008 protein_coding Mus_musculus 0 1256
ENSMUST00000113696 Tpm1-015 protein_coding Mus_musculus 0 1192
ENSMUST00000030185 Tpm1-002 protein_coding Mus_musculus 0 1177
ENSMUST00000113685 Tpm1-003 protein_coding Mus_musculus 0 1109
ENSMUST00000113693 Tpm1-011 protein_coding Mus_musculus 0 1098
ENSMUST00000113687 Tpm1-012 protein_coding Mus_musculus 0 1077
ENSMUST00000113695 Tpm1-016 protein_coding Mus_musculus 0 1048
ENSMUST00000139046 Tpm1-017 nonsense_mediated_decay Mus_musculus 0 989
ENSMUST00000129466 Tpm1-019 retained_intron Mus_musculus 0 865
ENSMUST00000129733 Tpm1-009 nonsense_mediated_decay Mus_musculus 0 822
ENSMUST00000113684 Tpm1-020 protein_coding Mus_musculus 0 819
ENSMUST00000113689 Tpm1-021 protein_coding Mus_musculus 0 819
ENSMUST00000131279 Tpm1-018 processed_transcript Mus_musculus 0 808
ENSMUST00000113686 Tpm1-014 protein_coding Mus_musculus 0 675
ENSMUST00000113690 Tpm1-013 protein_coding Mus_musculus 0 675
ENSDART00000039657 tpma-201 protein_coding Danio_rerio 0 612
ENSMUST00000107914 Tpm2-001 protein_coding Mus_musculus 0 464
ENSMUST00000030184 Tpm2-002 protein_coding Mus_musculus 0 451
ENSMUST00000107913 Tpm2-201 protein_coding Mus_musculus 0 412
ENSMUST00000150262 Tpm2-003 processed_transcript Mus_musculus 0 412
ENSMUST00000150592 Tpm2-004 protein_coding Mus_musculus 0 250
ENSMUST00000156899 Tpm1-005 processed_transcript Mus_musculus 2.8026e-45 187

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